I hope this isn't a complicated answer. You want the platform that has what games you want to play. Me personally I think the V32 is my favorite and has better game selection. (but I also have a 22/22)
As far as software is concerned, All Alpha 1 games (except Crystal Spider (v22/32) game will run on Alpha 2. Crystal Spider complains about the newer bios chip on Alpha 2 but plays fine on Alpha 1. Not a game worth worrying about.
If you get a v22/22 and run 22/32 game, the top screen will be sideways but still play fine. V32 runs sideways on a 22/22.
When buying games, look on youtube or ask on the forums if the game is 22/22, v32, curve, or v22/32.
If you get a V22/22 you can easily convert it to a curve, and back again. I do that with mine.
I could go on and on.. but tried to keep it simple.
Bottom line is the type of games you want to own.
Hope this helps